FDA News Update

FDA’s New Inspection Pilot Is Not Business as Usual

FDA is piloting one-day inspectional assessments — shorter, targeted “safety screening” visits, with facilities selected by artificial intelligence using risk-based criteria. Most early assessments closed…

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Registration and Listing Were Only the Beginning

MoCRA is no longer a registration-and-listing project. FDA’s January 2026 draft guidance on its records-access authority signals that the safety substantiation, adverse-event, and supplier records…

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The QMSR Is in Effect — This Is Compliance, Not Preparation

FDA’s Quality Management System Regulation (QMSR) took effect February 2, 2026, replacing the old Quality System Regulation and incorporating ISO 13485:2016 by reference. The framework is…

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FDA Real-Time Clinical Trials: What AI-Enabled Development Means for Sponsors (Comment by June 29)

FDA Is Moving Toward Real-Time Trial Oversight In April 2026, FDA announced major steps toward implementing real-time clinical trials (RTCT). Two developments anchor the initiative….

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After FDA’s ENDS Guidance: Why Importers and Retailers Still Face Enforcement Risk

FDA’s Guidance Is an Enforcement Policy, Not an Authorization On May 8, 2026, FDA issued Enforcement Priorities for Certain New Tobacco Products Marketed Without Premarket…

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MoCRA Cosmetic Facility Registration Renewals: What Brands Need to Know Before July 2026

If your cosmetic manufacturing facility registered with FDA in early 2024 — which is when the mandatory MoCRA registration deadline first hit — your renewal…

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FDA Issues New Enforcement Priorities for Unauthorized ENDS and Nicotine Pouch Products: What Manufacturers, Importers, and Retailers Should Know

FDA’s New Guidance Signals a More Targeted Enforcement Strategy for Vapes and Nicotine Pouches On May 8, 2026, the FDA issued final guidance titled “Enforcement…

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FDA QMSR Is Now in Effect: What Medical Device Companies Should Do Next

If you are a medical device company and you are still preparing for FDA inspections using the old Quality System Inspection Technique guide — stop….

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Flavored E-Cigarette PMTAs in 2026: What FDA’s New Draft Guidance Actually Changes

The FDA’s Center for Tobacco Products issued a new draft guidance on March 9, 2026, that is the most detailed statement yet on how the…

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FDA General Wellness Guidance 2026: What Wearable and Digital Health Companies Can and Can’t Do Now

If you’re building a wearable, wellness app, smart ring, recovery tracker, or connected health platform, FDA just updated the playbook — and the changes matter….

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Will the FDA Eliminate Self-Affirmed GRAS? What the Proposed Rule Could Mean

The conversation around self-affirmed GRAS is evolving quickly, with lawmakers and regulators signaling potential changes that could reshape how food ingredients are evaluated and brought…

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FDA GRAS Reform in 2026: What Food and Ingredient Companies Need to Know

The landscape of food ingredient safety is entering a period of significant transition in 2026. For decades, the “Generally Recognized as Safe” (GRAS) pathway has…

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