How FDA’s New AI System ELSA Is Revolutionizing Regulatory Review

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The U.S. Food and Drug Administration (FDA) has entered a new chapter in regulatory science with the introduction of ELSA—its generative AI tool designed to enhance how the agency reviews, interprets and processes regulatory information. As technology continues to reshape industries, even the most traditional and highly scrutinized government bodies are beginning to adopt AI…

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FDA’s 2025 Crackdown: How Unannounced Foreign Inspections Reshape Global Compliance

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The U.S. Food and Drug Administration (FDA) is stepping up its global oversight in 2025 with a game-changing initiative—unannounced inspections of foreign facilities. Designed to tighten compliance and protect the U.S. market from substandard imports, these surprise audits are set to disrupt the operations of overseas manufacturers supplying pharmaceuticals, medical devices, and food products.  If…

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Navigating 2025 Tariff Increases: FDA Compliance Strategies for Regulatory Success

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As 2025 unfolds, businesses operating in FDA-regulated industries are facing a fresh wave of challenges due to new tariff increases. These changes bring added pressure to pharmaceutical and medical device manufacturers, with potential implications on cost, supply chain efficiency, and regulatory compliance. Companies must now align their FDA compliance efforts with customs and trade requirements…

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FDA Flags Prohibited Methylene Chloride in Certain Gel Nail Polish Removers: Industry Takeaways

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On April 18, 2025, the FDA issued a public notice identifying several gel nail polish removers containing methylene chloride, a chemical banned in cosmetic products under 21 CFR 700.19. This action underscores the agency’s continued enforcement focus on prohibited substances in cosmetics and signals heightened scrutiny of non-compliant imports. Key Findings FDA testing revealed that…

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BREAKING: FDA v. Wages and White Lion Investments, LLC: A Key Supreme Court Opinion on E-Cigarette Regulation

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In a recent decision, the U.S. Supreme Court addressed a significant case involving the Food and Drug Administration (FDA) and the regulation of flavored electronic nicotine delivery systems (e-cigarettes). This ruling, which examines the FDA’s authority under the Family Smoking Prevention and Tobacco Control Act of 2009 (TCA), has wide-ranging implications for how the agency…

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Why FDA Staff Losses Are a Public Health Concern

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The recent wave of staff reductions at the U.S. Food and Drug Administration (FDA) has raised urgent questions about the Agency’s ability to fulfill its critical mission. The FDA is more than just another government entity—it is the backbone of the nation’s public health infrastructure, responsible for ensuring the safety of $2.6 trillion in consumption…

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